Thermo Fisher Scientific Logo
      • Popular
      • Applications & Techniques
      • Shop All Products
      • Services
      • Support
      • Sign in
      • Quick Order

      Search Thermo Fisher Scientific

      Search All
      search

      Advancing analytical workflows for prohibited substance detection in equine athletes using software tools

      • Overview
      • About the presenters

      Despite advances in analytical chemistry, it is becoming increasingly challenging to control prohibited substance abuse in equine athletes. A problem is the ever-increasing number of prohibited substances, resulting in the need for large custom-made compound databases and mass spectral libraries.

      In this webinar, we discuss the development of a >440 compound screen, with a custom-built mass spectral library and compound database along with the transfer of this method from a Thermo Scientific Orbitrap Exploris 480 MS to a Thermo Scientific TSQ Altis mass spectrometer for confirmation. We demonstrate the integration of multiple software tools including mzCloud, mzVault and Thermo Scientific TraceFinder SW for a holistic view of method development beyond analytical capabilities.

      Key learning objectives

      • Understand the analytical challenges of confidently detecting and identifying prohibited substances
      • Discover how integrated software tools can drive rapid method development from a discovery environment, through to routine screening and confirmation
      • See how connected hardware platforms and software tools aid in method transfer, and help to advance analytical workflows to combat the issues of prohibited substance detection
      • Better understand how a connected laboratory is now a reality, and can help with small molecule compound identification and quantitation workflow deployment

      Who should attend

      Researchers and leaders in Academia, bio/pharma, clinical, forensic toxicology, and protein research; any laboratories who are focused on both small molecule and protein identification and quantitation workflows, where there is the need to transfer knowledge from research through to routine.

      • Lab Directors and industry experts responsible for setting new standards, and when needed, demonstrate success in challenging or high-profile work.
      • Technology Leaders responsible for the competitive edge while improving productivity and efficiency with highly trained operators.
      • Principle Scientists in screening and quantitative applications: needing the best technology to advance their research discoveries and develop new testing methodologies.
      Scott Stanley, Ph.D., Professor in Equine Toxicology and Pharmacology, Department of Veterinary Science and Director of the Equine Analytical Chemistry Laboratory, University of Kentucky

      Scott Stanley, Ph.D., Professor in Equine Toxicology and Pharmacology, Department of Veterinary Science and Director of the Equine Analytical Chemistry Laboratory, University of Kentucky

      Dr. Stanley received his doctoral degree in Toxicology in 1992, and his bachelor’s degree in Animal Science in 1988 from the University of Kentucky. He was a faculty member at University of California-Davis since 1997 through 2018. At UC-Davis, Dr. Stanley was the chief chemist of the Kenneth L. Maddy Equine Analytical Chemistry Laboratory. He modernized drug testing in California horse racing by introducing new, state-of-the-art instrumental drug testing equipment and procedures. He has also worked closely with manufactures in adapting newer technologies to equine drug testing. Dr. Stanley moved to the University of Kentucky in early 2019, his current research interests are related to drug testing methods for the detection of biopharmaceuticals, natural products and designer drugs, and the establishment of the Equine Biological Passport project.

      Sophie Bromilow, Ph.D., Scientist III at Equine Analytical Research Laboratory, University of Kentucky

      Sophie Bromilow, Ph.D., Scientist III at Equine Analytical Research Laboratory, University of Kentucky

      Dr. Bromilow received her doctoral degree in Biology, Medicine and Health focused on Proteomics in 2018 from the University of Manchester, and her bachelor’s degree in Chemistry 2013 from the University of Liverpool. Following the completion of her Ph.D Dr. Bromilow joined UC Davis under Dr. Stanley’s supervision to undertake Post-Doctoral Research. During this time, Dr. Bromilow applied her proteomics expertise to Equine Anti-Doping Strategies and began to establish the Equine Biological Passport, showing the first proof of concept for the use of biomarkers as indicators of prohibited substance abuse. Dr. Bromilow has since continued her research under Dr. Stanley’s supervision at the University of Kentucky.

      Overview

      Despite advances in analytical chemistry, it is becoming increasingly challenging to control prohibited substance abuse in equine athletes. A problem is the ever-increasing number of prohibited substances, resulting in the need for large custom-made compound databases and mass spectral libraries.

      In this webinar, we discuss the development of a >440 compound screen, with a custom-built mass spectral library and compound database along with the transfer of this method from a Thermo Scientific Orbitrap Exploris 480 MS to a Thermo Scientific TSQ Altis mass spectrometer for confirmation. We demonstrate the integration of multiple software tools including mzCloud, mzVault and Thermo Scientific TraceFinder SW for a holistic view of method development beyond analytical capabilities.

      Key learning objectives

      • Understand the analytical challenges of confidently detecting and identifying prohibited substances
      • Discover how integrated software tools can drive rapid method development from a discovery environment, through to routine screening and confirmation
      • See how connected hardware platforms and software tools aid in method transfer, and help to advance analytical workflows to combat the issues of prohibited substance detection
      • Better understand how a connected laboratory is now a reality, and can help with small molecule compound identification and quantitation workflow deployment

      Who should attend

      Researchers and leaders in Academia, bio/pharma, clinical, forensic toxicology, and protein research; any laboratories who are focused on both small molecule and protein identification and quantitation workflows, where there is the need to transfer knowledge from research through to routine.

      • Lab Directors and industry experts responsible for setting new standards, and when needed, demonstrate success in challenging or high-profile work.
      • Technology Leaders responsible for the competitive edge while improving productivity and efficiency with highly trained operators.
      • Principle Scientists in screening and quantitative applications: needing the best technology to advance their research discoveries and develop new testing methodologies.
      About the presenters
      Scott Stanley, Ph.D., Professor in Equine Toxicology and Pharmacology, Department of Veterinary Science and Director of the Equine Analytical Chemistry Laboratory, University of Kentucky

      Scott Stanley, Ph.D., Professor in Equine Toxicology and Pharmacology, Department of Veterinary Science and Director of the Equine Analytical Chemistry Laboratory, University of Kentucky

      Dr. Stanley received his doctoral degree in Toxicology in 1992, and his bachelor’s degree in Animal Science in 1988 from the University of Kentucky. He was a faculty member at University of California-Davis since 1997 through 2018. At UC-Davis, Dr. Stanley was the chief chemist of the Kenneth L. Maddy Equine Analytical Chemistry Laboratory. He modernized drug testing in California horse racing by introducing new, state-of-the-art instrumental drug testing equipment and procedures. He has also worked closely with manufactures in adapting newer technologies to equine drug testing. Dr. Stanley moved to the University of Kentucky in early 2019, his current research interests are related to drug testing methods for the detection of biopharmaceuticals, natural products and designer drugs, and the establishment of the Equine Biological Passport project.

      Sophie Bromilow, Ph.D., Scientist III at Equine Analytical Research Laboratory, University of Kentucky

      Sophie Bromilow, Ph.D., Scientist III at Equine Analytical Research Laboratory, University of Kentucky

      Dr. Bromilow received her doctoral degree in Biology, Medicine and Health focused on Proteomics in 2018 from the University of Manchester, and her bachelor’s degree in Chemistry 2013 from the University of Liverpool. Following the completion of her Ph.D Dr. Bromilow joined UC Davis under Dr. Stanley’s supervision to undertake Post-Doctoral Research. During this time, Dr. Bromilow applied her proteomics expertise to Equine Anti-Doping Strategies and began to establish the Equine Biological Passport, showing the first proof of concept for the use of biomarkers as indicators of prohibited substance abuse. Dr. Bromilow has since continued her research under Dr. Stanley’s supervision at the University of Kentucky.

      Register to view the free
      on-demand webinar

      * Required field

      *
      *
      *
      *
      *
      *
      *
      *
      *
      *

       I would like to speak with an expert to learn how Thermo Fisher Scientific products can help in my laboratory
       Please confirm you would like to receive marketing and promotional email messages about Thermo Fisher Scientific products and services.
       
       

      Resources

      • Learn more about the Orbitrap Exploris 480 mass spectrometer
      • eBook: Strategies for Making Small Molecule Unknowns Known
      • Watch more LC-MS webinars
      • Technical Note: Building Curated and Annotated HRAM MSn Spectral Libraries to Aid in Unknown Structure Elucidation
      • White Paper: Delivering confidence for small molecule Identification
      • Smart Note: Accelerate small-molecule unknown identification
      •  
      •  
      •  
      •  
      •  
      •  
      Brands
      •  
      Shopping Tools
      • Product Selection Guides
      • Quick Order
      • Redeem a Quote
        * Please enter a valid quote
      • New Products
      • Promotions
      • Mobile & Desktop Apps
      • Shared Lists
      • Check Order Status
      eSolutions
      • eProcurement
      • Supply Center
      • Instrument Management
      Support
      • Check Order Status
      • Order Support
      • Training
      • Webinars
      • Blog
      • Social Media
      • Contact Us
      • Report a Site Issue
      Thermo Fisher Scientific
      • About Us About Us
      • Careers Careers
      • Investors Investors
      • News News
      • Responsibility
      • Trademarks
      • Terms & Conditions
      • Privacy Information Center
      • Price & Freight Policy

       

      • Thermo Fisher Scientific Inc. announces acquisition of QIAGEN N.V., a leading global provider of molecular diagnostics and sample preparation technologies. Learn more ›

      • Custom Logo
      Sign in

      Don't have an account ? Create Account

    • Aspire Member Program
    • Connect: Lab, Data, Apps
    • Custom Products & Projects
    • Instrument Management
    • Services Marketplace
    • Account
    • Check Order Status
      • Popular
          • Popular
            • TaqMan Real-Time PCR Assays TaqMan Real-Time PCR Assays
            • Antibodies Antibodies
            • Oligos, Primers & Probes Oligos, Primers & Probes
            • GeneArt Gene Synthesis GeneArt Gene Synthesis
            • Cell Culture Plastics Cell Culture Plastics
      • Applications & Techniques
        • See Links For Applications & Techniques
          • Brands
            • See Links For Brands
            • Thermo Scientific
            • Applied Biosystems
            • Invitrogen
            • Fisher Scientific
            • Unity Lab Services
          • Life Sciences
            • See Links For Life Sciences
            • Antibodies
            • Cell Analysis
            • Cell Culture & Transfection
            • Cloning
            • DNA & RNA Extraction & Analysis
            • Epigenetics & ncRNA Research
            • Flow Cytometry
            • Gene Expression Analysis & Genotyping
            • Genome Editing
            • Microarray Analysis
            • Oligos, Primers, Probes, & Genes
            • PCR
            • Protein Biology
            • Real-Time PCR
            • RNAi
            • Sequencing
            • Stem Cell Research
            • Synthetic Biology
          • Industrial & Applied Sciences
            • See Links For Industrial & Applied Sciences
            • Agrigenomics
            • Animal Health
            • Bioprocessing
            • Cement, Coal & Minerals
            • Chromatography
            • Drug Discovery & Development
            • Electron Microscopy
            • Environmental
            • Food & Beverage
            • Forensics
            • Geosciences
            • Manufacturing & Processing
            • Mass Spectrometry
            • Materials Science
            • Microbiology
            • Pharma & Biopharma
            • Radiation Detection & Measurement
            • Safety & Security Threat Detection
            • Spectroscopy, Elemental & Isotope Analysis
          • Clinical & Diagnostics
            • See Links For Clinical & Diagnostics
            • Anatomical Pathology
            • Biobanking
            • Cancer Research
            • Cell & Gene Therapy
            • Clinical Genomics
            • Clinical Microbiology
            • Clinical & Translational Research
            • Diagnostic Development
            • Diagnostic Testing
            • Precision Medicine
            • Preclinical to Companion Diagnostic Development
            • Public Health
          • Lab Solutions
            • See Links For Lab Solutions
            • Chemicals
            • Digital Solutions
            • Informatics
            • Lab Automation
            • Lab Data Management & Analysis Software
            • Lab Equipment
            • Lab Plasticware & Supplies
            • Sample Storage & Management
      • Shop All Products
        • See Links For Shop All Products
          • Save up to 50% off cell biology products  
          • Save up to 30% off lab products  
          • Upgrade your gel tanks for $10  
          • Save up to 22% on western blotting  
          • Most Popular Products
            • Beakers
            • Lab Centrifuges
            • Ultra Low–Temperature Freezers
            • Lipofectamine Reagents
            • Nalgene Labware
            • Oligos, Primers, Probes & Nucleotides
            • Pipettes & Pipette Tips
            • SuperScript Reverse Transcriptase
            • TaqMan Real-Time PCR Assays
            • TRIzol Reagents
          • Most Popular Categories
            • Antibodies & Immunoassays
            • Cell Culture & Transfection Reagents
            • Chromatography Columns, Resins, & Spin Filters
            • Drug Discovery Assays
            • Gels & Membranes
            • Instruments & Equipment
            • Lab Reagents & Chemicals
            • Lab Supplies, Plastics & Glassware
            • Primers/Oligos, Cloning & Gene Synthesis
            • Software & Digital Storage
          • Order Tools
            • How to Order
            • Quick Order
            • Track Your Order
            • Order History
            • Order Support
            • Contact Us
          • Shop All Products
            • See Links For Shop All Products
            • Product Selection Guides
            • New Products
            • Promotions
            • Online Offers
      • Services
        • See Links For Services
            • Services Marketplace
            • Custom Services
            • Enterprise-Level Lab Informatics
            • Enterprise Services
            • Financial & Leasing Services
            • Instrument Services
            • OEM & Commercial Supply
            • Training Services
      • Support
        • See Links For Support
          • Product Documentation
            • Manuals
            • Safety Data Sheets (SDS)
            • Certificates of Analysis & Conformance
            • CE Declarations of Conformity
            • RoHS Certificates
            • Manufacturing Site ISO Certifications
          • Other Product Information
            • Citations & References
            • Product Literature
            • Vector Maps
            • Chemical Structures
            • Spectral Data
            • Media Formulations
          • Product Support
            • Knowledge Base & FAQs
            • Instrument Support
            • Support Centers
            • Contact Us
          • Educational Resources
            • Learning Centers
            • Digital Transformation
            • Gibco Cell Culture Basics
            • Protein Methods Library
            • Supplemental Protocols
            • Newsletters & Journals
            • Training Services
            • Events
          • Popular Tools & Calculators
            • Lab Apps for Mobile Devices
            • Oligos Tools & Utilities Hub
            • Tm Calculator for PCR
            • Molecular Biology Tools
            • Gibco Media Formulation Tool
            • Cell Culture Useful Numbers
            • Fluorescence SpectraViewer
            • Flow Cytometry Panel Builder
            • Cell Staining Tool
            • Protein Gel Conversion Tool
            • Switch to Nunc Plastics Tool
            • Transfection Protocol Calculator